OEIS complex – a rare developmental anomaly

OEIS complex

OEIS is a malformative complex that associates an omphalocele, an exstrophy of the cloaca, an anal imperforation and spinal defects. Normal development of the cloaca gives origin to the lower abdominal wall with bladder, intestine and anus, genitals organ and part of the pelvis bones and lumbosacral spine. Incidence of OEIS is rare, thought to occur in 1 in 200,000 to 1 in 250,000 live births. ...

OEIS Complex, A Case Report

Introduction: The OEIS complex includes: Omphalocele, Exstrophy of the cloaca, Imperforate anus, and Spinal defects. The OEIS complex affects 1 in 200,000 to 400,000 pregnancies and its etiology is uncertain. The purpose is to present our experience in this unusual coexistence of malformations never reported in Latin America. Clinical Case: A male infant, three months of age, diagnosed at birth...

Ghost Teeth: A Rare Developmental Anomaly of the Dental Tissues

Regional odontodysplasia (RO) is a sporadic (not inherited) developmental defect involving only a few contiguous teeth in a small region of the jaw; developmentally it involves both mesodermal and ectodermal dental components. It affects the primary and permanent dentition in the maxilla and mandible or both jaws. Generally it is localized to only one arch. The etiology of this dental anomaly i...

OEIS Complex: developmental insights into a severe congenital abnormality of body wall development

Thanatophoric Dysplasia; a Rare Case Report on a Congenital Anomaly

The rare form of skeletal dysplasia is thanatophoric dysplasia. The meaning for thanatophoric dysplasia is death bearing which is derived from Greek word. It occurs 1in 20,000 to 50,000. It is mainly due to mutations in the fibroblast growth factor receptor 3gene. Features of thanatophoric dysplasia are frontal bossing, prominent eyes, narrow thorax, protruded abdomen and bowed legs. The knowle...